Interní Med. 2008; 10(2): 58-61

What is the situation in the treatment of patients with hypertension and metabolic syndrome?

doc. MUDr. Miroslav Souček CSc

II. interní klinika FN u sv. Anny LF MU, Brno

Combination of clinical and metabolic factors that constitute metabolic syndrome has been explored thoroughly because of its high and constantly increasing prevalence in general population and clear relation of the syndrome to increased prevalence of cardiovascular diseases. The most important intervention is a life style change (dietary and physical activity modification), however in a number of patients further intervention including pharmacotherapy is indicated to influence blood pressure, obesity, lipids and blood sugar. The basic treatment of hypertension includes the blockade of renin-angiotensin system (ACE-inhibitors, sartans), that are frequently combined with other antihypertensive medications preferably metabolically neutral.

Keywords: metabolic syndrome, cardiovascular risk, renin-angiotensin system, ACE-inhibitors, sartans, metabolically neutral antihypertensives

Published: May 1, 2008  Show citation