Interní Med. 2009; 11(7): 355-357

Indication for examination of risk factors for venous thrombosis

MUDr. Miloslava Matýšková CSc1, MUDr. Marie Šlechtová2, prof. MUDr. Miroslav Penka CSc3
1 Bakešova chirurgická nemocnice Brno
2 Oddělení klinické hematologie FN Brno
3 Oddělení klinické hematologie, FN Brno

Pathogenesis of thrombosis is based on multiple factors. In past years many interacting factors were described, both inherited and

environmental. Surveying these should be indicated only in cases where knowledge of the defect can influence patient’s treatment or

prophylaxis. We should examine only factors in which there is a proven relation to clinical picture. We should always take family and

personal history into account while interpreting the results.

Keywords: thrombophilia, venous thrombosis, laboratory examination.

Published: September 1, 2009  Show citation

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Matýšková M, Šlechtová M, Penka M. Indication for examination of risk factors for venous thrombosis. Interní Med. 2009;11(7):355-357.
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References

  1. Walker ID, Greaves M, Preston FE on behalf of the Haemostasis and Thrombosis Task Force British Committee for Standards in Hematology. Investigation and management of heritable thrombophilia. Br J Haematol 2001; 114: 512-528. Go to original source... Go to PubMed...
  2. Rosendaal FR. Risk factors for venous thrombotic disease. Thromb Haemost 1999; 82: 610-619. Go to original source... Go to PubMed...
  3. Greaves M, Baglin T. Laboratory testing for heritable thrombophilia: impact on clinical management of thrombotic disease. Br J Haematol 2000; 109: 699-703. Go to original source... Go to PubMed...
  4. Jick H, Slone D, Westerholm B, et al. Venous thromboembolic disease and AB0 blood group type. A cooperative study. Lancet 1969; 1: 539-542. Go to original source... Go to PubMed...
  5. Matýšková M, Zavřelová J, Pejchalová A, et al. Krevní skupiny AB0 a faktor V Leiden. Čas lék čes 2002; 141 (5): 146-151.
  6. Matýšková M, Paseka J, Vorlová Z, et al. Prevalence of factor V Leiden mutation in healthy women. In: Scharrer I, Schramm W. 29. Hämophilie - Symposion Hamburg 1998, Springer 1999: 309-311. Go to original source...
  7. Dulíček P, Malý J, Kalousek I, et al. Výskyt venózního tromboembolizmu u žen s Leidenskou mutací v souvislosti s graviditou a šestinedělím. Čes Gynekol 2005; 70 (2): 133-138.
  8. Kist WJ, Janssen NG, Kalk JJ, et al. Thrombophilias and adverse pregnancy outcome - A confound problem! Thromb Haemost 2008; 88: 77-85. Go to original source... Go to PubMed...
  9. Ho WK, Hankey GJ, Quinlan DJ, Eikelboom JW: Risk of recurrent venous thromboembolism in patients with common thrombophilia. Arch Intern Med 2006; 166: 729-736. Go to original source... Go to PubMed...
  10. Rossi E, Za T, Ciminello A, et al. The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia. Thromb Haemost 2008; 15 (6): 1030-1034. Go to original source... Go to PubMed...
  11. Van Boven HH, Vandenbroucke JP, Briët E, Rosendaal FR. Gene-gene and gene-enviromental interactions determine risk of thrombosis in families with inherited antithrombin deficiency. Blood 1999; 94 (8): 2590-2594. Go to original source...
  12. Legnani C, Cosmi B, Cini M, et al: High plasma levels od factor VIII and risk of recurrence of venous thromboembolism. Br J Hameatol 2004; 124: 504-510. Go to original source... Go to PubMed...
  13. Matýšková M, Šlechtová M, Zavřelová J, Penka M. Combined FV Leiden and antithrombin deficiency in women. Thrombosis Res 2009; 123 (Suppl 2): S155, Abstract P55. Go to original source...
  14. Blanco-Molina Á, Trujillo-Santos J, Tirado R, et al. Venous thromboembolism in women using hormonal contraceptives. Findings from the RIETE Registry. Thromb Haemost 2009; 15 (3): 478-482. Go to original source...
  15. van Vlijmen EF, Brouwer JL, Veeger NJ, et al. Oral contraceptives and the absolute risk of venous thromboembolism in women with single or multiple thrombophilic defects: results from a retrospective family cohort study. Arch Intern Med 2007; 167: 282-289. Go to original source... Go to PubMed...
  16. Dalen, JE. Should patients with venous thromboembolism be screened for thrombophilia? Am J Med 2008; 121: 458. Go to original source... Go to PubMed...
  17. Tormene D, et al. The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study. Blood 2002; 100 (7): 2403-2405. Go to original source... Go to PubMed...
  18. De Stefano V, Rossi E, Paciaroni K, Leone G. Screening for inherited thrombophilia: indications and therapeutic implications. Haematologica 2002; 87: 1095-1108. Go to original source... Go to PubMed...
  19. Atherosclerosis, Thrombosis, and Vascular Biology Italian Study Group: No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age. Circulation 2003; 107: 1117-1122. Go to original source... Go to PubMed...
  20. Tondeur S, Boutruche S, Biron-Andréani C, Schved J-F. Prevalence of the Jak2 V617F mutation associated with splanchnic vein thrombosis. A 10-year retrospective study. Thromb Haemost 2009; 101: 787-789. Go to original source... Go to PubMed...




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