Interní Med. 2001; 3(7): 309-312

Význam hyperaktivity sympatiku u kardiovaskulárních chorob

doc. MUDr. Miroslav Souček CSc1, MUDr. Tomáš Kára2, MUDr. Petr Fráňa1, MUDr. Ivan Řiháček1, MUDr. Marek Orban2
1 II. interní klinika FN u sv. Anny LF MU, Brno
2 I. interní kardioangiologická klinika FN u sv. Anny v Brně

Keywords: autonomic nervous systém, tachycardia, renin-angiotensin systém, metabolic syndrom.

Published: December 31, 2001  Show citation

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Souček M, Kára T, Fráňa P, Řiháček I, Orban M. Význam hyperaktivity sympatiku u kardiovaskulárních chorob. Interní Med. 2001;3(7):309-312.

Tento stručný přehled shrnuje důkazy o klíčové roli zvýšené aktivity sympatiku ve vzniku a přetrvávání kardiovaskulárních nemocí. Výsledky experimentálních výzkumů jednoznačně podporují názor, že zvýšená aktivita sympatiku je těsně spojena s patogenezí řady koronárních rizikových faktorů včetně zvýšené koagulace, vaskulární hypertrofie, hypertrofie levé komory, inzulinové rezistence a dyslipidémie.

The Importance of Sympathetic Hyperactivity in Cardiovascular Diseases

This brief review summarizes proofs of the key role of increased sympathetic activity in origin and outlasting of cardiovascular disorders. Results of experimental studies support unambiguously an idea, that an increased sympathetic activity is closely connected to pathogenesis of lots of coronary risk factors including increased coagulation, vascular hypertrophy, left ventricle hypertrophy, insulin resistance and dyslipidemias.

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    References

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