Interní Med. 2002; 4(4): 177-180

Management diagnostiky a terapie bronchogenního karcinomu - II. díl

doc. MUDr. Miloš Pešek CSc1,2, Jindřich Fínek3, MUDr. Petr Mukenšnabl4
1 Klinika nemocí plicních a tuberkulózy, FN Plzeň
2 Fakultní nemocnice Plzeň
3 Chirurgická klinika FN Plzeň
4 Šiklův patologicko-anatomický ústav, LF UK a FN v Plzni

Keywords: lung cancer, chemotherapy, radiotherapy, concomitant chemoradiotherapy, supportive therapy, treatment of complications due to chemotherapy, dispensary.

Published: December 31, 2002  Show citation

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Pešek M, Fínek J, Mukenšnabl P. Management diagnostiky a terapie bronchogenního karcinomu - II. díl. Interní Med. 2002;4(4):177-180.

V druhé části souborného sdělení se autoři zabývají zásadami chemoterapie nemalobuněčného i malobuněčného karcinomu plic. Seznamují čtenáře s vyšetřeními, která je nutné provést před zahájením onkologické terapie a uvádějí i základní léčebná schémata, užívaná v současnosti. Jako perspektivní se jeví kombinace chemoterapie s radioterapií, zejména pak konkomitantní chemoradioterapie.

U malobuněčných karcinomů jsou uvedeny aktuální perspektivy nemocných v závislosti na stádiu onemocnění i základní léčebné kombinace a zásady radioterapie.

Autoři vymezují roli dalších odborníků v týmu pečujících o nemocné s bronchogenním karcinomem, kteří se podílejí na různých fázích terapie včetně léčby komplikací a terapie podpůrné. Je zde zdůrazněna především úloha praktického lékaře.

Novým směrem v terapii bronchogenního karcinomu je tzv. biologicky cílená léčba, která využívá inhibice buněčných receptorů, např. receptoru pro epidermální růstový faktor.

V závěru článku jsou uvedena preventivní opatření a základní posudková pravidla u nemocných po skončení onkologické léčby.

Management of diagnosis and treatment of lung cancer - Part 2

In Part 2 of the review the authors continue with the principles of chemotherapy of non-small cell and small cell lung cancer. They present the diagnostic procedures which are needed to perfrom before the initiation of the oncological therapy and basic treatment regimens. A combination of chemotherapy and radiotherapy, especially concomitant chemoradiotherapy, appears to have a good prospect. In small cell lung cancer the current prospect for patients depends on the stage of the disease and the basic treatment combination and principles of radiotherapy are also described. The authors define the role of other specialists in the team who contribute to the care of patients with lung cancer during the different phases of the treatment, including management of complications and the provision of a supportive care. The emphasis is on the role of the general practitioner. Biologically-targeted therapy, an example of which is the blocking of access of growth factors, such as the epidermal growth factor, to their cell receptors, represents a novel trend in the management of lung cancer.

The authors conclude with some preventive measures and the basic assessment rules for patients after completion of their oncological therapy.

Klinika nemocí plicních a tuberkulózy FN Plzeň

Radioterapeutické oddělenní FN Plzeň

Šiklův patologicko-anatomický ústav FN Plzeň

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