Interní Med. 2003; 5(3): 131-137

Imunoterapie u alergie a astmatu

doc. MUDr. Petr Panzner CSc
Ústav imunologie a alergologie LF UK a FN Plzeň

Keywords: allergy, asthma, allergen immunotherapy, anti-IgE.

Published: December 31, 2003  Show citation

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Panzner P. Imunoterapie u alergie a astmatu. Interní Med. 2003;5(3):131-137.

Účinnost injekční alergenové imunoterapie u alergické rhinitidy a astmatu byla jednoznačně prokázána mnoha studiemi. Tato léčba zlepšuje kvalitu života pacientů, snižuje potřebu další medikace a zlepšuje funkční parametry u astmatu. Snižuje riziko rozvoje astmatu u pacientů s alergickou rhinitidou a snižuje riziko rozšíření senzibilizace na další alergeny. Do budoucna se jeví perspektivní další imunoterapeutické postupy, např. léčba monoklonální protilátkou anti-IgE, jejíž zavedení do praxe se očekává v blízké budoucnosti.

Imunotherapy of allergy and asthma

Clinical efficacy of allergen immunotherapy was shown in many clinical trials for allergic rhinitis and asthma. Allergen immunotherapy improves quality of life and decreases medication requirement for allergic rhinitis and asthma and will assist in the prevention of the progression of allergic disease from rhinitis to asthma. It decreases also the risk of polysenzitization. There are other immunotherapeutic procedures with high benefit potential, e.g. anti-IgE monoclonal antibody, which practical use is expected in the near future.

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