Interní Med. 2004; 6(12): 583-585

Perforace gastroduodenálního vředu

MUDr. David Charvát, MUDr. Jaromír Šimša
Chirurgická klinika UK 2. LF a FN Motol, Praha

Keywords: perforated peptic ulcer, active diagnostic approach, urgent surgical treatment.

Published: December 31, 2004  Show citation

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Charvát D, Šimša J. Perforace gastroduodenálního vředu. Interní Med. 2004;6(12):583-585.

I v současnosti je perforace gastroduodenálního vředu významnou chirurgickou břišní příhodou vyžadující až na výjimky neodkladnou operaci. Klinický termín peptický vřed zahrnuje všechny vředové projevy gastroduodenální sliznice a také i jiných úseků sliznice trávicího ústrojí, jako jsou jícen a jejunum, které přicházejí do styku s účinkem žaludeční kyseliny a pepsinu. Ačkoliv konzervativní farmakologická léčba nekomplikované vředové choroby je velmi úspěšná, zůstává počet pacientů s komplikací vředové choroby - perforací gastroduodenálního vředu prakticky stejný a počet úmrtí pacientů s touto komplikací u lidí starších než 65 let má spíše stoupající tendenci. Stanovení diagnózy a léčba pacientů s perforací gastroduodenálního vředu si zasluhuje stále nejvyšší pozornost.

Gastroduodenal ulcer perforation

Gastroduodenal ulcer perforation is a serious surgical abdominal event requiring, except some exceptions, urgent surgery even at present. Clinical term peptic ulcer covers all ulcerous manifestations of gastroduodenal mucous membrane, but also in other parts of digestive tract mucosa such as oesophagus and jejunum, which are in contact with the action of gastric juice and pepsin. Although the conservative pharmacological treatment of uncomplicated ulcerous disease is very effective, the quantity of patients with ulcerous disease complications, gastroduodenal ulcer perforations, remains almost the same and the number of patients age more than 65 and dying with this complication has rather increasing frequency. Establishing a diagnosis and a treatment in patients with gastroduodenal ulcer perforation still deserves the highest attention.

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References

  1. Gilliam AD, Speake WJ, Lobo DN, Beckingham IJ. Current practice of emergency vagotomy and Helicobacter pylori eradication for complicated peptic ulcer in the UK. Br. J. Surg. 2003; 90 (1): 80-90. Go to original source... Go to PubMed...
  2. Uccheddu A, Floris G, Altana ML, Pisanu A, Cois A, Farci SL. Surgery for perforated peptic ulcer in the elderly. Evaluation of factors influencing prognosis. Hepatogastroenterology. 2003; 50 (54): 1956-1958. Go to PubMed...
  3. Testini M, Portincasa P, Piccinni G, Lissidini G, Pellegrini F, Greco L. Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer. World J Gastroenterol. 2003; 9 (10): 2338-2340. Go to original source... Go to PubMed...
  4. Bartkowski R, Endrich B, Siess M. DRG exercises: perforated duodenal ulcer, peritonitis. Chirurg 2002; 73 (12): M 357-360. Go to PubMed...
  5. Hermansson M, Stael von Holstein C, Zilling T. Surgical approach and prognostic factors after peptic ulcer perforation. Eur J. Surg. 1999; 165 (6): 566-572. Go to original source... Go to PubMed...
  6. Holscher AH, Gutschow C, Schafer H, Bollschweiler E. Conventional surgery in peptic ulcer perforation: indications and procedure. Kongressbd Dtch bes Chir. Kongr. 2001; 118: 285-288. Go to original source...
  7. Noguiera C, Silva AS, Santos JN, Silva AG, Ferreira J, Matos E, Vilaca H. Perforated peptic ulcer: main factors of morbidity and mortality. World J. Surg. 2003; 27 (7): 782-787. Go to original source... Go to PubMed...
  8. Morris PJ, Wood WC. Oxford Textbook of Surgery. 2nd ed. Oxford; New York: Oxford University Press, 2000.
  9. Hoch J, Leffler J, a kol. Speciální chirurgie. 2. vydání. Maxdorf Jessenius 2003.
  10. Černý Ján. Špeciálna chirurgia 1. Chirurgia tráviacej rúry. Osveta, 1990.
  11. Neville Woolf. Pathology. Basic and Systemic. W.B. Saunders Company Ltd., 1998.
  12. Lawrence W. Way a kol. Současná chirurgická diagnostika a léčba. Grada Publishing, 1998.
  13. Chen CH, Huang HS, Yang CC, Yeh YH. The features of perforated peptic ulcers in conventional computed tomography. Hepatogastroenterology 2001; 48 (41): 1393-1396. Go to PubMed...
  14. Lee FYJ, Leung KL, Lai BSP, Ng SSM, Dexter S, Lau WY. Predicting mortality and morbidity of patients operated on for perforated peptic ulcers. Arch Surg 2001; 136: 90-94. Go to original source... Go to PubMed...




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