Interní Med. 2005; 7(9): 392-394

Bronchogenic carcinoma: new trends in diagnosis and therapy

prof. MUDr. Miloš Pešek CSc
Klinika nemocí plicních a tuberkulózy, FN Plzeň

The author presents basic epidemiologic data concerning lung cancer, its symptoms and population at risk. The essential of diagnosis in the suspected cases are a history, physical exam, chest X-ray in 2 projections, bronchoscopy and computed tomography of the chest. In the article we can find technical and staff requirements for equipment of a centre for diagnosis and treatment of bronchogenic carcinoma. The author emphasizes especially interdisciplinary approach. Internists and cardiologists play an important role in preoperative preparation of patients, general practitioners in diagnosis and therapy.The author suggests an algorithm of therapeutic steps in non-small cell and small cell lung carcinoma and modern trends in diagnosis and therapy (adjuvant chemotherapy after surgery, functional imaging of tumours, roles of first and second line chemotherapy, prophylactic radiotherapy of brain and he mentions also a new approach – biologically targeted therapy. At the end of the article the author describes a role of tobacco and discuses aetiology of exceptionally poor prognosis of lung cancer.

Keywords: Key words: bronchogenic carcinoma, chemotherapy, radiotherapy, surgical treatment, adjuvant chemotherapy, biologically targeted therapy.

Published: January 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Pešek M. Bronchogenic carcinoma: new trends in diagnosis and therapy. Interní Med. 2005;7(9):392-394.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Alberg AJ, Brock MV, Samer JM. Epidemiology of Lung Cancer: Looking to the Future. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3175-3185. Go to original source... Go to PubMed...
    2. Česká onkologická společnost ČLS JEP: Zásady cytostatické léčby maligních onkologických onemocnění. Brno, 15. 6. 2005.
    3. Farray D, Mirkovic N, Albain KS. Multimodality Therapy for Stage III Non-Small-Cell Lung Cancer. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3257-3269. Go to original source... Go to PubMed...
    4. Jähne PA, Engelman JA, Johnson BE. Epidermal Growth Factor Receptor Mutations in Non-Samll-Cell Lung Cancer: Implications for Treatment and Tumor Biology. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3227-3234. Go to original source... Go to PubMed...
    5. van Meerbeeck J, Schil PV, Kramer G, et al. A randomized trial of radical surgery (S) versus thoracic radiotherapy (TRT) in patients (pts) with stage IIIA-N2 non-small cell lung cancer (NSCLC) after response to induction chemotherapy (ICT) (EORTC 08941). Lung Cancer, Vol. 49, Suppl. 2, 2005, s. S4 No Pr5. Go to original source...
    6. Meyerson M, Carbone D. Genomic and Proteomic Profiling of Lung Cancers: Lung Cancer Classification in the Age of Targeted Therapy. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3219-3226. Go to original source... Go to PubMed...
    7. Patel JD. Lung Cancer in Women. Journal of Clinical Oncology, 2005; Vol. 23, Number 14: 3212-3218. Go to original source... Go to PubMed...
    8. Pešek M. Aktualizace doporučených léčebných postupů u nemalobuněčného bronchogenního karcinomu. Stud. Pneumol. Phthiseol., 64, 2004; 3: 144-150.
    9. Pešek M, et al. Bronchogenní karcinom. Galén Praha 2002, ISBN 80-7262-115-7, 235.
    10. Pisters KMW, Le Chevalier T. Adjuvant Chemotherapy in Completely Resected Non-Small-Cell Lung Cancer. Journal of Clinical Oncology, Vol. 23, No. 14, 2005, str. 3270-3278. Go to original source... Go to PubMed...
    11. Shankar LK, Sullivan DC. Functional Imaging in Lung Cancer. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3203-3211. Go to original source... Go to PubMed...
    12. Shepherd FA. A Targeted Approach to Reducing Lung Cancer Mortality. Journal of Clinical Oncology, 2005; Vol. 23, No. 14: 3173-3174. Go to original source... Go to PubMed...
    13. Ústav zdravotnických informací a statistiky ČR 2005, NOR ČR: Novotvary 2002 ČR.
    14. Zatloukal P. Chemoterapie karcinomu plic. Farmakoterapie 1/2005; 76-80.

    Return to the content


    Internal Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.