Interní Med. 2006; 8(5): 231-234
Peptic gastric and duodenal ulcer disease - current trends of treatment
- III. interní klinika gastroenterologická, FN Brno-Bohunice
Current treatment of peptic ulcer disease is based on limitation of the effect of aggressive factors, in particular hydrochloride acid, presence of H. pylori bacteria on mucosa of stomach and drug related damage to gastric mucosa. The importance of diet is smaller than expected years ago, diet is individualized and contains exclusion of generally known irritating components of diet and smoking. Drugs are dominated by proton pump inhibitors. Medications are the first choice in therapy of uncomplicated ulcers and basic treatment in eradication of H. pylori. In prevention of damage of gastric mucosa, e.g. by medications (nonsteroidal anti-inflammatory drugs). The intravenous application enabled the morbidity decline of patients with acute gastrointestinal bleeding. Proton pump inhibitors are safe in therapeutic doses in patients with peptic ulcers.
Keywords: Key words: peptic ulcer disease, H. pylori infection, proton pump inhibitors.
Published: June 1, 2006 Show citation
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