Interní Med. 2006; 8(9): 401-404

Ibandronát (Bonviva) v léčbě postmenopauzální osteoporózy

MUDr. Tomáš Hála
Ústav zdravotnických studií, Univerzita Pardubice, Pardubice

Osteoporóza je civilizační choroba a představuje velký problém medicínský, ekonomický a sociální. Následkem osteoporózy dochází ke zlomeninám, z nichž hlavně zlomeniny obratlů a krčku stehenní kosti vedou k nárůstu morbidity a mortality. Odhaduje se, že přibližně 70 % pacientek je v současné době nediagnostikovaných a neléčených, nebo jsou léčeny nedostatečně. Je zarážející, že ani po výskytu zlomeniny u pacienta nebývá pravidlem zahájení správného vyšetřovacího a léčebného postupu. Při takovéto situaci je logický nárůst komplikací, zejména fraktur. Hlavním cílem léčby je zabránit zlomeninám, mezi další cíle patří zachování množství a kvality kostní hmoty nebo dosažení jejich úpravy, dále též zmírnění klinických důsledků fraktur a deformit skeletu a zachování tělesné zdatnosti. Nízká adherence k léčbě je výrazný problém v péči o pacienty s osteoporózou. Následkem je zvýšené riziko zlomenin. Prodloužením dávkovacího intervalu lze adherenci k léčbě zlepšit. Ibandronát (Bonviva) je nový účinný aminobisfosfonát v prevenci a terapii postmenopauzální osteoporózy. Výhodou je podávání 150 mg ibandronátu 1x měsíčně, což snižuje možný výskyt nežádoucích účinků a zvyšuje adherenci pacienta k terapii.

Keywords: Klíčová slova: osteoporóza, adherence k léčbě, ibandronát.

Published: March 1, 2007  Show citation

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Hála T. Ibandronát (Bonviva) v léčbě postmenopauzální osteoporózy. Interní Med. 2006;8(9):401-404.
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