Interní Med. 2007; 9(2): 70-74

Approach for the antibiotic therapy of respiratory infections

MUDr. Václava Bártů

Pneumologická klinika, Fakultní Thomayerova nemocnice a 1. lékařská fakulta UK, Praha

Upper and low respiratory tract infections belong among the most frequent diseases of childhood and adults and this situation is connected with high prescription and usage of antibiotics. Knowledge of local bacteriological situation of workplace, local drug resistance, national and international recommendations for therapy of respiratory diseases play important role in the choice of the optimal antibiotic drug. The basis requirement for select drug is its efficiency, safety and quality in the clinical practice which leads to the suppression of the bacterial infection. If the bacterial origin of the disease is documented the rational therapy is based on the drug sensitivity tests. Increa­sing use of antibiotics is directly followed by increasing bacterial resistance. Unsubstantiated antibiotic therapy in the bad-founded cases makes the situation wrong and it leads to the decreasing antibiotic efficiency. This strategy increases costs of the effective treatment of respiratory infections. Detailed knowledge of effective spectrum, mechanism of drug penetration into the infection place, local epidemiological situation form the basis presumptions for the optimal antibiotic choice. National and international standards provide the specific recommendations for therapy of respiratory infections.

Keywords: Key words: antibiotics, respiratory infections, clinical efficiency, resistance.

Published: March 1, 2007  Show citation