Interní Med. 2007; 9(3): 124-128
Retention of fluid with congestion, hypervolemia, and volume overload of heart are regular components of syndrome of advanced heart failure. The principle of the diuretic effect is the increase of urine formation as a consequence of the interference with transport mechanisms of chlorides, sodium, potassium and water on the level of tubuli and collecting ducts in kidneys. The article discusses pathophysiological and clinical consequences of congestion, strategies of diuretic therapy and its influence on morbidity and mortality of patients with heart failure.
Published: April 1, 2007 Show citation