Interní Med. 2007; 9(5): 221-224

Screening of sporadic colorectal cancer in Czech republic

prof. MUDr. Přemysl Frič DrSc1, doc. MUDr. Miroslav Zavoral Ph.D1, MUDr. Bohumil Seifert2, MUDr. Petr Pokorný3, MUDr. Štěpán Suchánek3,4
1 Interní klinika 1. LF UK a Ústřední vojenské nemocnice, subkatedra gastroenterologie IPVZ, Praha
2 Ústav všeobecného lékařství, 1. LF UK, Praha
3 Všeobecná zdravotní pojišťovna, Praha
4 Interní klinika 1. LF UK a ÚVN Praha

Czech Republic occupies the top position in world statistics of colorectal cancer (CRC) incidence. Approximately 8 000 new cases and 5 000 deaths are recorded yearly. These losses are unnecessary, because CRC belongs to the best treatable tumors, if disclosed at an early stage. Pilot trials of CRC screening in Czech Republic started in 1979. Two prospective open studies including more than 120 000 probands as well as a cost-benefit evaluation were performed in the years 1985-1991 and 1997-1998. Population screening of CRC was started on July 1st 2000. The two-step testing consists of a guaiac fecal occult blood test (gFOBT) and colonoscopy in gFOBT-positive subjects. The eligible population includes asymptomatic subjects since 50 years of age. Screening is performed at two years interval as part of a free preventive check-up. The expenses are reimbursed to general practitioners by health insurance companies. A total of 139 926 colonoscopies were performed in 2005 at digestive endoscopy units in all 14 regions 0indings included 951 CRC and 4 682 subjects with polyps removed during 5 672 endoscopic polypectomies. These figures correspond to 16.7 %, 17.8 %, and 16.0 % of values found in the total colonoscopic series. The findings confirm the significance of the two-step screening program for early diagnosis of colorectal neoplasia in Czech population.

Keywords: colorectal cancer, population screening, Czech Republic

Published: June 21, 2007  Show citation

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Frič P, Zavoral M, Seifert B, Pokorný P, Suchánek Š. Screening of sporadic colorectal cancer in Czech republic. Interní Med. 2007;9(5):221-224.
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References

  1. Bond JH. Fecal occult blood testing for colorectal cancer. Can we afford not to do this? Gastroenterol Clin N Am 1997; 26: 57-69. Go to original source... Go to PubMed...
  2. Bond JH. The place of fecal occult blood testing in colorectal cancer screening in 2006: the U.S. perspective. Am J Gastroenterol 2006; 101: 219-221. Go to original source... Go to PubMed...
  3. Coffield AB, Maciosek MV, McGinnis JM, et al: Priorities among recommended preventive services. Am J Prev Med 2001; 21: 1-9. Go to original source... Go to PubMed...
  4. European Group for Colorectal Cancer Screening. Recommendation to include colorectal cancer screening in public health policy. Sevilla Meeting, 13th-14th November 1998.
  5. Frič P. The use of Haemoccult test in the early diagnosis of colorectal cancer - experience from six pilot studies in Czechoslovakia. In: Hardcastle JV: Haemoccult screening for the early detection of colorectal cancer. Schattauer, Stuttgart, 1986: 73-74.
  6. Frič P, Zavoral M, Dvořáková H, et al. An adapted program of colorectal cancer screening - 7-years experience and cost-benefit analysis. Hepato-Gastroenterology 1994; 41: 413-416. Go to PubMed...
  7. Frič P, Zavoral M, Čekal J, et al. Screening kolorektálního karcinomu v současném systému zdravotní péče (Pražský projekt). Endoskopie 1999; 8: 39-45.
  8. Gnauck R. World Health Organization criteria for screening. In: Winawer SJ, Schottenfield D, Sherlock P (vyd): Colorectal cancer: prevention, epidemiology and screening. Raven Press, New York, 1980: 175-180.
  9. Hardcastle JD, Chamberlain JO, Robinson MHE, et al. Randomised controlled trial of faecal occult blood screening for colorectal cancer. Lancet 1996; 348: 1472-1477. Go to original source... Go to PubMed...
  10. Kronborg O, Fenger C, Olson J, et al. Randomised study of screening for colorectal cancer with fecal occult blood test. Lancet 1996: 348: 1467-1771. Go to original source... Go to PubMed...
  11. Maciosek MV, Coffield AB, Edwards NM, et al. Priorities among effective clinical preventive services: results of a systematic review and analysis. Am J Prev Med 2006; 31: 52-61. Go to original source... Go to PubMed...
  12. Mandel JS, Bond JH, Church TR, et al. Reducing mortality from colorectal cancer by screening for occult blood. New Engl J Med 1993; 328: 1472-1477. Go to original source... Go to PubMed...
  13. Seifert B. Proveditelnost testu na okultní krvácení ve stolici v ordinacích praktických lékařů. Čes a Slov Gastroent a Hepatol 2005; 59: 105-107.
  14. Sung J: Does fecal occult blood have a place for colorectal cancer screening in China in 2006? Am J Gastroenterol 2006; 101: 213-215. Go to original source... Go to PubMed...
  15. US Preventive Services Task Force. Guide to clinical preventive services. Ed. 2. US department of health and human services. Washington, DC, 1995.
  16. Wagner JL, Tunis S, Brown M, et al: Cost-effectiveness of colorectal cancer screening in average-risk adults. In: Young G, Rozen P, Brown M et al: Prevention and early detection of colorectal cancer. Saunders, Philadelphia, 1996: 321-356.
  17. Winawer SJ, Zauber AG. The advanced adenoma as the primary target of screening. Gastrointest Endosc Clin N Am 2002; 12: 1-9. Go to original source... Go to PubMed...




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