Interní Med. 2007; 9(6): 268-272
Combination of diabetes mellitus (DM) and thyroid disease (TD) is more frequent than their prevalence in general population (5–7 percents). DM is found in 10–20 % patients with TD, in Graves thyrotoxicosis in 20–25 percent. The effective treatment is normalization of thyroid function, that can prevent in early stage the development of permanent DM. In diabetic patients TD is frequent in autoimmune DM (DM 1, LADA) the autoimmune TD prevails (chronic autoimmune thyroiditis). Pathalogic changes of thyroid function (hypo – and/or hyperthyroidism) impair metabolic compensation of DM and increase a risk of its complications. Most important is combination of DM and TD in pregnancy, where it is dangerous for both health status of mother and development of fetus.
Published: November 9, 2007 Show citation