Interní Med. 2007; 9(9): 386-388

The impact of smoking on morphology and function of cardiovascular system

MUDr. Lubor Goláň1,2
1 II. interní klinika kardiologie a angiologie 1. LF UK a VFN, Praha
2 II. interní klinika, VFN, Praha

Smoking is a major cardiovascular risk factor. It affects adversely morphology and function of cardiovascular system. Endothelial dysfunction, disturbances of hemostasis based on platelet activation and decreased function of endogenous fibrinolytic system, activation of inflammation, hemodynamic changes and increased oxygen demand are triggered by tobacco smoke. Smokers tend to be insulin resistant and suffer from disorders of lipid metabolism. The result of complex changes is acceleration of atherosclerosis with all negative consequences. Passive smoking also constitutes a significant risk. Non-smokers can be exposed to environmental tobacco smoke at work or at home, that is why a ban on smoking on public ground, protection of employees, and education are essential.

Keywords: smoking, tobacco smoke, cardiovascular risk, atherosclerosis, endothelial dysfunction, insulin resistance

Published: January 1, 2008  Show citation

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Goláň L. The impact of smoking on morphology and function of cardiovascular system. Interní Med. 2007;9(9):386-388.
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