Interní Med. 2008; 10(1): 31-34
Infection caused by Varicella-zoster virus and its therapy
- Klinika dětských infekčních nemocí FN a LF MU, Brno
Herpes zoster (shingles) is an inflammatory disease of spinal ganglia and posterior medullar roots or cranial nerves that is cause by reactivation of herpetic Varicella-zoster virus (VZV). First infection with the virus manifests most frequently in childhood as a generalized eruption of typical exanthema – varicella (chicken pox). Shingles presents with typical skin eruption in corresponding involved dermatomes and algic syndrome mainly in predisposed individuals, who are mainly older adult people and especially immunocompromised and oncology patients. The infection causes long-term or persistent sequelae quite frequently in the form of postherpetic neuralgia.
Keywords: Varicella-zoster virus, varicella, herpes zoster, postherpetic neuralgia
Published: April 1, 2008 Show citation
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