Interní Med. 2008; 10(3): 113-116

News in the gluten-free diet

doc. MUDr. Pavel Kohout CSc
II. interní klinika, Thomayerova nemocnice, Praha

Celiac disease is an autoimmune disease, its manifestation starts in genetically predisponed individuals after gluten ingestion. During transmission of toxic gliadin peptides through small bowel mucosa and its deamidations (by action of tissue transglutaminase from enterocytes) are formel in gut associated lymphatic tissue antibodies against enterocytes. Its activity leads to small bowel mucosa damage of various relevance and formation of clinical symptoms. The manifestations of celiac disease may be influenced only with elimination of toxic gliadin peptides for the diet, at this time are the other ways than searching of new gluten-free foodstufs.

Keywords: celiac disease, gluten-free diet, gluten, gliadin, prolamine

Published: May 1, 2008  Show citation

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Kohout P. News in the gluten-free diet. Interní Med. 2008;10(3):113-116.
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