Interní Med. 2008; 10(3): 117-120
New guidelines of diagnosis and treatment of lipid disorders in adulthood, prepared by the committee of the Czech society of atherosclerosis are based on results of new epidemiological and interventional studies with hypolipidemics and on new knowledge on pathophysiology of lipid disorders. They introduce new recommended target levels of LDL-cholesterol, inform about the use of apolipoprotein and non-HDL cholesterol as secondary targets in selected groups of individuals (with diabetes mellitus, metabolic syndrome, hypertriglyceridemy, cardiovascular disease with relatively low level of LDL-cholesterol). They improve the estimation of individual risk of cardiovascular complications taking into account both classical and some of new risk factors and present also the options of detection of preclinical atherosclerosis. Priorities of treatment, algorhytms of treatment of individual disorders (monotherapy and combination of hypolipidemics) are discussed as well as nonpharmacological intervention in patients with lipid disorders.
Published: May 1, 2008 Show citation