Interní Med. 2008; 10(4): 167-171

Treatment of invasive fungal infections

MUDr. Zdeněk Ráčil¹, Mgr. Iva Kocmanová², MUDr. Barbora Weinbergerová¹, MUDr. Šárka Bohatá³, MUDr. Jana Winterová¹, prof. MUDr. Jiří Mayer CSc¹

¹ Interní hematoonkologická klinika LF MU a FN Brno

² Oddělení klinické mikrobiologie, Fakultní nemocnice Brno, pracoviště Bohunice

³ Radiologická klinika, LF MU a FN Brno

The frequency of invasive fungal infections has significantly increased over the last two decades with the rise in at-risk populations of patients. The morbidity and mortality of deep fungal infections are high and management of these infections is difficult. The epidemiology of invasive fungal pathogens has also changed. Non-albicans Candida, Aspergillus spp. and moulds other than Aspergillus have become increasingly recognised causes of invasive diseases. Recently developed antifungal agents, such as second-generation triazoles and echinocandins, provide the potential to improve management options and therapeutic outcomes of these infections. This article reviews the role of available antifungal agents in the management of invasive fungal infections.

Keywords: invasive fungal infections, treatment, antifungals

Published: May 1, 2008  Show citation