Interní Med. 2008; 10(6): 273-276

ACE-inhibitors or sartans in coronary heart disease?

prof. MUDr. Jindřich ©pinar CSc., FESC, prof. MUDr. Jiří Vítovec CSc
I. interní kardioangiologická klinika FN u sv. Anny v Brně

We review the current knowledge in ACE-inhibitors and angiotensin II receptor 1 blockers in patients with coronary heart disease. The data from clinical trials in hypertension revealed some advantages of ACE-inhibitors, however results of direct comparison of large multicentric trial ONTARGET confirms the assumption that both pharmaceutical groups are effective, safe and comparable, but the combination of ACE-inhibitors and AII antagonists is probably not advisable. The blockade of system renin-angiotensin-aldosteron is a base of treatment of patients in secondary prevention of coronary heart disease. Only further studies will show on what level it is the most advantageous to block the whole system.

Keywords: Key words: ACE inhibitors, AII antagonists, hypertension, coronary heart disease.

Published: July 1, 2008  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
©pinar J, Vítovec J. ACE-inhibitors or sartans in coronary heart disease? Interní Med. 2008;10(6):273-276.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article


    Return to the content


    Internal Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.