Interní Med. 2009; 11(1): 16-20
Etiology and pathogenesis of Crohn´s disease remains not completely understood. It is unquestionable interaction between the environmental
and genetically susceptible individual. New genes are being describe, but the functional consequences of gene mutations
are not known. New classifications of Crohn´s disease are searching interaction between fenotype and genotype of the disease and
serological markers. Capsule endoscopy and enteroscopy improved detection of small intestinal lesions. In medical therapy the early
use of imunosuppresives and biologic therapy have significant effect on quality of life.
Published: March 1, 2009 Show citation