Interní Med. 2009; 11(6): 288-290

Chronic venous insufficiency and venotonics

MUDr. Ivo Hofírek
I. interní klinika, FN u sv. Anny, Brno

The paper deals with chronic venous insufficiency, its incidence, causes, and treatment options including the administration of venotonics.

They are evaluated by comparing information from the literature, actual clinical papers, and the practice. Venotonics play a supplemental

role in the treatment of chronic venous insufficiency which consists in managing edema, reducing unpleasant sensations in individual

cases, and, secondarily, improving the perceived quality of life.

Keywords: venous insufficiency, venotonics.

Published: July 1, 2009  Show citation

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Hofírek I. Chronic venous insufficiency and venotonics. Interní Med. 2009;11(6):288-290.
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    References

    1. O´Donnell TF jr, Welch HJ. Chronic venous insufficiency and varicose veins. In Peripheral vascular diseases, 2nd ed., edited by Young JR, Olin JW, Bartholomew JR. Mosby-Year Book, St. Louis 1996.
    2. Ruckley CV. Socioeconomic impact of chronic venous insufficiency and leg ulcers. Angiology 1997; 48: 67-69. Go to original source... Go to PubMed...
    3. Simka M, Majewski E. The social and economic burden of venous leg ulcers: focus on the role of micronized purified flavonoid fraction adjuvant therapy. Am J Clin Dermatol. 2003; 4 (8): 573-581. Go to original source... Go to PubMed...
    4. Puchmayer V, Roztočil K. Onemocnění žil in Praktická angiologie. Triton, Praha 2000: 115-164.
    5. Tibbs DJ. Varicose veins and related disorders. Butterworth-Heinemann Ltd., Oxford 1992.
    6. Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med. 1991; 151: 933-938. Go to original source...
    7. International Task Force. The management of chronic venous disorders of the leg: an evidence-based report. Phlebology 1999; 14 (Suppl 1): 23-34.
    8. Brand FN, Dannenberg AL, Abbott RD, Kannel WB. The epidemiology of varicose veins: the Framingham Study. Am J Prev Med. 1988; 4 (2): 96-101. Go to original source...
    9. Leu HJ, Lie JT. Diseases of the veins and lymphatic vessels, including angiodysplazia. In Vascular pathology, edited by Stehbens WE and Lie JT. Chapman & Hall Medical, London 1995: 489-516.
    10. Navrátilová Z. Diferenciální diagnostika hyperosmolárních otoků dolních končetin. Med Pro Praxi 2006; 6: 281-283.
    11. Musil D. Otoky dolních končetin. Prakt. lékařství 2003: 126-128.
    12. Horáková M. Kompresivní terapie ve flebologii. Novinky v medicíně 52: 51-84. Avicenum. Praha 1990.
    13. Martinez MJ, Bonfill X, Moreno RM, Vargas E, Capell? D. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2005; 20 (3): CD003229. Go to original source... Go to PubMed...
    14. Boada JN. Therapeutic Effect of Venotonics in Chronic Venous Insufficiency Clin Drug Invest 1999; 18 (6): 413-432. Go to original source...
    15. Coleridge-Smith P, Lok C, Ramelet AA. Venous leg ulcer: a meta-analysis of adjunctive therapy with micronized purified flavonoid fraction. Eur J Vasc Endovasc Surg. 2005; 30 (2): 198-208. Go to original source... Go to PubMed...
    16. Cesarone MR, Belcaro G, Pellegrini L, Ledda A, Vinciguerra G, Ricci A, Di Renzo A, Ruffini I, Gizzi G, Ippolito E, Fano F, Dugall M, Acerbi G, Cornelli U, Hosoi M, Cacchio M. Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency. Angiology 2006; 57 (2): 131-138. Go to original source... Go to PubMed...
    17. Bamigboye AA, Hofmeyr GJ.Interventions for leg edema and varicosities in pregnancy. What evidence? Eur J Obstet Gynecol Reprod Biol. 2006; 129 (1): 3-8. Epub 2006 May 4. Go to original source... Go to PubMed...
    18. Bamigboye AA, Smyth R. Interventions for varicose veins and leg oedema in pregnancy. Cochrane Database Syst Rev. 2007; 24 (1): CD001066. Go to original source... Go to PubMed...
    19. Frick RW. Three treatments for chronic venous insufficiency: escin, hydroxyethylrutoside, and Daflon. Angiology 2000; 51 (3): 197-205. Go to original source... Go to PubMed...
    20. Šárník S, Hofírek I, Panovský R. Monitoring functional disorders of microcirculation using laser doppler flowmetry in patients with chronic venous insufficiency class 2 according to CEAP classification before and after varicose veins surgery. Vnitřní lékařství 2007; 53 (12): 1286-1295. Go to PubMed...
    21. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. The Cochrane Database Syst. Rev. 2007. Go to original source... Go to PubMed...
    22. Zemková M, Vlček J. Mechanismy účinku frekventně užívaných léčiv a jejich terapeutická hodnota - venofarmaka. Praktické lékárenství 2005; 1: 13-15.

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