Interní Med. 2009; 11(9): 405-409
The overwiev of current knowledges of toxic shock syndrome. Toxic shock syndrome is a multiorgan disease caused by toxins that is
characterized by rapid onset of shock and significant lethality. Two microbes are included in the etiology of the disease. Staphylococcus
aureus producing TSST-1 and enterotoxins cause staphylococcal toxic shock syndrome. Strains of Streptococcus pyogenes that involve
some M proteins and produce pyrogen exotoxins cause streptococcal toxic shock syndrome. The pathogenesis of both types of infection,
clinical picture, diagnosis and differential diagnosis, treatment and possible prophylactic measures are described.
Published: October 1, 2009 Show citation