Interní Med. 2009; 11(12): 558-560

Gastrointestinal polypous syndromes

MUDr.Přemysl Falt, MUDr.Petr Fojtík, MUDr.Martin Kliment
Centrum péče o zažívací trakt, Vítkovická nemocnice, a. s., Ostrava

Colorectal carcinoma is one of the most frequent neoplastic diseases. In about 5 % of patients, it is caused by genetically defined syndromes.

Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are the most important ones. Polypous syndromes

are characterised by the development of numerous polyps of the colorectal mucosa but also of another parts of the digestive tract.

From a histological point of view polyps are either premalignant adenomas or hamartomas with low risk of malignant transformation.

However, hamartomatous syndromes are associated with increased risk for extraintestinal tumors.

Keywords: hereditary colorectal cancer, polypous syndromes, familial adenomatous polyposis

Published: May 1, 2010  Show citation

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Falt P, Fojtík P, Kliment M. Gastrointestinal polypous syndromes. Interní Med. 2009;11(12):558-560.
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