Interní Med. 2009; 11(12): 561-568

Nutrition and secondary osteoporosis

MUDr.Petr Fojtík¹, MUDr.Ondřej Urban¹, MUDr.Přemysl Falt¹, MUDr.Pavel Novosad²

¹ Centrum péče o zažívací trakt, Vítkovická nemocnice, a. s., Ostrava

² Mediekos a. s., Osteologické centrum, Zlín

Nutrition has a significant impact on bone health throughout life. Proper nutritional status is essential for bone mass growth in

childhood and adolescence. Moreover, it is necessary for maintaining the bone mass during the life. An adequate intake of calcium,

vitamin D and vitamin K is essential in the treatment of osteoporosis. Recently, the positive effect of vitamin K2 on osteokalcin has

been discovered. Additionally, the impact of proteins, omega 3 fatty acids, vitamins and other trace elements on bone metabolism

has been conformed. Secondary osteoporosis is more frequent than expected, with the prevalence of 30–60 % in men and 50 % in

perimenopausal women. The most frequent postmenopausal osteoporosis might be combined with secondary osteoporosis and

diagnosing and treating these patients might be challenging. Main cause of secondary osteoporosis are gastrointestinal diseases

such as inflammatory bowel diseases (Crohn´s disease, ulcerative colitis), coeliac disease, chronic cholestatic liver diseases, patients

after gastric and intestinal surgery, pancreatic exocrine insufficiency, lactose intolerance and glucocorticosteroids treatment. Patients

with osteoporosis are usually treated by osteologists, patients with gastrointestinal diseases by gastroenterologists. Since these

patients have both osteoporosis and digestive disease the collaboration between gastroenterologists and osteologists is necessary

to diagnose and treat these patients properly.

Keywords: nutrition, osteoporosis, secondary osteoporosis, coeliac disease, lactose intolerance, vitamin K2

Published: May 1, 2010  Show citation