Interní Med. 2010; 12(3): 131-135

Allergic rhinitis, diagnosis and therapy

MUDr.Zuzana Humlová

Ústav imunologie a mikrobiologie 1. LF UK a VFN, Praha

Allergic rhinitis is the most common diagnose among atopic diseases in the population. Its previous classification on to seasonal allergic

rhinitis and perennial allergic rhinitis has been abandoned. Contemporary classification is based on intensity of symptoms, their

duration and an impact of quality of life. The most important allergens are pollen grains, moulds, mites, animal danders, occupational

allergens, food and drugs. Etiopathogenesis of allergic rhinitis is based on IgE – mediated response of organism onto frequent contact

with an allergen. Eosinophilic inflammation is then the final result of this activation. Suppression of the inflammation is the first-line task.

Symptomatic therapy represents mostly using of antihistamines and nasal corticosteroids. In indicating cases we use specific allergen

immunotherapy which is potentially a causal therapy.

Keywords: allergic rhinitis, eosinophilic inflammation, antihistamines, nasal corticosteroids, allergen immunotherapy

Published: May 1, 2010  Show citation