Interní Med. 2010; 12(3): 136-139

Management of resistant hypertension

MUDr.Filip Málek, Ph.D., MBA

Kardiologické oddělení, Nemocnice Na Homolce, Praha

Despite the progress of the therapy and target organ damage diagnostics in the patiens with arterial hypertension, issue of resistant

hypertension is still actual. The prevalence of resistant hypertension, which is defined as the inability to reach target blood pressure

values with three antihypertensiv drugs diuretics included, is about 30 % in hypertensive subjects. After exclusion of the secondary

hypertension, when the most common cause are: primary hyperaldosteronism, chronic kidney disease and renovascular hypertension,

the main cause of the resistant hypertension are: white coat phenomenon, poor life-style control, low adherence of the patients to the

therapy and drug interactions. The management of the resistant hypertension belongs to the specialists in internal medicine, cardiologists,

eventually nephrologists. The main principle of the treatment of the resistant hypertension is elimination of the causes leading

to not reaching blood pressure goals, and the pharmacotherapy according to the actual guidelines for the management of the arterial

hypertension.

Keywords: hypertension, resistance, pharmacotherapy, secondary hypertension, pseudohypertension, pseudoresistance

Published: May 1, 2010  Show citation