Interní Med. 2010; 12(4): 220-222

Prevention of acute kidney injury: what is available in clinical practice

prof.MUDr.Martin Matějovič, Ph.D.

I. interní klinika FN Plzeň a LF v Plzni, Univerzita Karlova v Praze

Acute kidney injury (AKI) is a complication that occurs frequently in hospitalized patients. AKI is associated with significant mortality

and morbidity. The first step in prevention is to identify persons at high risk for AKI. In this context, patients with chronic kidney disease,

atherosclerosis, diabetes mellitus, chronic heart failure and/or poor nutrition are at particular risk. The most common precipitating factors

for the development of AKI include sepsis, major surgery (in particular cardiac and vascular surgery), marked hypovolemia, severe

pancreatitis, nephrotoxic drugs and radiocontrast media. Renal protection should focus on prompt resuscitation of the circulation,

maintaining adequate blood pressure, and avoidance of any nephrotoxins.

Keywords: acute kidney injury, acute renal failure, prevention, resuscitation, diuretics

Published: May 1, 2010  Show citation