Interní Med. 2010; 12(10): 510-515
Cancer diseases are mostly polyfactorial, but in 5–10 % of cases the disease may be of hereditary origin. Mutations in a high-risk gene are
transmitted from generation to generation and increase the probability of cancer occurrence many times. Genetic examination should
be indicated in families with repeated cancer, especially in young age, with multiple malignancies, with combination of rare cancers. In
families where the disease is probably not hereditary, the prevention in relatives is also important, evaluation of the risk and offering
a preventive care is important. This follow-up of relatives of cancer patients is not routinely done.
Published: November 15, 2010 Show citation