Interní Med. 2011; 13(1): 24-27

Strategy of anticoagulant and antiplatelet therapy in cardiac disease

doc.MUDr.Petr Heinc, Ph.D., doc.MUDr.Miloš Táborský, CSc., FESC, MBA, MUDr.David Vindiš

I. interní klinika Fakultní nemocnice Olomouc

Atrial fibrillation, acute coronary syndrome and congestive heart failure are frequent cardiac disease with significant enhancement of

thrombembolic complications. Different strategies of anticoagulant or antiplatelet therapy in patient with atrial fibrillation are recommended

in prevention of thrombembolic complications according to presentation of different risk factors. Long lasting antiplatelet

therapy with aspirin is principal in patients with coronary artery disease. Dual antiplatelet therapy with aspirin and clopidogrel is indicated

in patient with acute coronary syndrom for 1 month up to 1 year according to type of stent implantation. Different strategies of antithrombotic

therapy are proposed in acute coronary syndrom with different concomitant thrombembolic risk. The choice of antiplatelet

or anticoagulant therapy is postulated in patient with congestive heart failure according to severity of heart failure and presentation of

concomitant thrombembolic risk factors, first of all atrial fibrillation and ischemic heart disease.

Keywords: atrial fibrillation, antithrombotic treatment, CHA2DS2Vasc score, acute coronary syndrome, congestive heart failure

Published: January 14, 2011  Show citation