Interní Med. 2012; 14(3): 107-110

Chronic kidney disease

MUDr.Jan Vachek^1,2, MUDr.PhDr.Oskar Zakiyanov^1,3, prof.MUDr.Vladimír Tesař, DrSc., MBA¹

¹ Klinika nefrologie 1. LF UK a VFN, Praha

² Farmakologický ústav 1. LF UK, Praha

³ Ústav lékařské biochemie a laboratorní diagnostiky 1. LF UK a VFN, Praha

Chronic kidney disease (CKD) is a serious public health issue with far-reaching medical and social consequences including the enormous

cost to the public health system. Since the patients with CKD frequently present with small subjective symptomatology, the condition

is recognized late in many cases. Given the global demographics and the dramatic expansion in the number of patients with CKD and

associated diseases, a working knowledge of this renal disease is a prerequisite for the practicing physicians including primary care

physicians and specialists. The present review aims to assist a clinician to day-to-day manage of patients with CKD and introduces the

issues from the epidemiology, etiology, and risk factors of end-stage kidney disease progression. Furthermore, the review introduces

the currently used classification of CKD, describes clinical picture and provides the diagnosis options of this condition. The article also

mentions the current options of renal replacement therapy and depicts the novel approaches in therapy of CKD patients.

Keywords: chronic kidney disease (CKD), hemodialysis, peritoneal dialysis, renal transplant

Published: March 26, 2012  Show citation