Interní Med. 2012; 14(10): 362-364

Antiinflammatory properties of statins

MUDr.Peter Riško, doc.MUDr.Pavel Kraml Ph.D., Bc.Jana Potočková, MUDr.Jana Střížová
II. interní klinika FNKV, Praha

Statins have been extensively prescribed for its ability to reduce blood cholesterol level and positive impact on cardiovascular diseases.

In recent years, increased evidence of its pleiotropic effects – antioxidant, antithrombotic, anti-inflammatory, immunomodulatory

effect, possible anti-foam cell effect and improving of endothelial dysfunction. In this review, is outlined possible mechanism of antiinflammatory

and immunomodulatory effect of statins.

Keywords: statin, prenylation, small GTP proteins, immunity

Published: November 1, 2012  Show citation

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Riško P, Kraml P, Potočková J, Střížová J. Antiinflammatory properties of statins. Interní Med. 2012;14(10):362-364.
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