Interní Med. 2012; 14(11): 419-421

Hypercalcaemia in praktice

prof.MUDr.Ivana Žofková, DrSc.
Endokrinologický ústav, Praha

In this review foundamental physiological and pathophysiological aspects of clacaemia regulation are mentioned. Syptomatology,

consequences and treatment of hypercalcaemia, incl. hypercalcaemic cisis, are discussed. Attention is focused on primary hyperparathyroidism,

which is, together with malignant diseases, the most frequent cause of hypercalcaemia (90 %). In diferential diagnosis malignant

and granulomatous diseases, renal failure, endocrinopathies, effect of drugs or immobilization and benign familiar hypocalciuric

hypercalcaemia (caused by inactivation mutation in calcium – sensing receptor gene) are necessary to exclude. At the end of the article

the step diagnostic procedure in hypercalcaemia is outlined.

Keywords: hypercalcaemia, hyperparathyroidism, granulomatous diseases, malignant diseases, familiar hypocalciuric hypercalcaemia

Published: December 1, 2012  Show citation

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Žofková I. Hypercalcaemia in praktice. Interní Med. 2012;14(11):419-421.
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