Interní Med. 2012; 14(11): 443-446
Systemic connective tissue diseases and their complications
Systemic connective tissue diseases are chronic conditions that, in addition to the musculoskeletal system (joints, tendons, and muscles),
can affect numerous other organs, including the skin, heart, lungs, kidneys, nervous system, eyes, and digestive tract. They include
rheumatoid arthritis, systemic lupus erythematosus, systemic scleroderma, myositis, Sjögren’s syndrome, vasculitides and others. In the
early period of the disease, complications most often arise that are related to the degree of organ involvement; in the late period, they
develop as a result of long-term organ damage or due to adverse effects of long-term immunosuppressive therapy. These complications
are mostly very severe, life-threatening conditions with a poor prognosis (sepsis, pulmonary and renal involvement).
Sjögren’s syndrome.
Published: December 1, 2012 Show citation