Interní Med. 2012; 14(12): 455-457
The treatment of chronic rhinosinusitis (CRS) represents a major problem given the prevalence of this condition in the population
and the resulting socioeconomic impacts. The etiology and pathogenesis of CRS are discussed. The treatment involves both conservative
and surgical methods. In addition to the standardly used topical steroids, conservative therapy mainly employs so-called
immunolides (e.g. erdosteine), systemic pharmaceuticals that block the mediators involved in the complex chain of CRS development.
Surgical treatment, with the exception of complications, is regarded as second-choice modality, with modern technological
procedures being used, such as FESS (functional endoscopic sinus surgery), a microsurgical mini-invasive method with minimal
morbidity for the patient.
erdosteine.
Published: January 1, 2013 Show citation