Interní Med. 2013; 15(6-7): 210-213

Growth hormone treatment in adulthood

doc.MUDr.Zdeněk Fryšák, CSc., doc.MUDr.David Karásek, Ph.D., MUDr.Milan Halenka, Ph.D.

3. interní klinika &ndash, nefrologická, revmatologická a endokrinologická FN a LF UP Olomouc

The growth hormone deficiency in adulthood became a separate clinical entity in 1997. Then the growth hormone therapy gradually penetrated

into the clinical practice. Many questions was raised as for its effects despite increasing experience and length of time, of course.

As it turns out, not all of them have been fully answered, up till now. Anyway, appropriate selection of patients suitable for the growth hormone

therapy in adulthood should be strictly demanded. An original scheme under which it is possible to set up the appropriate replacement

dose to the patient exists. Recent years gradually have dissipated doubts stemming from the possibility of adverse consequences of longterm

growth hormone replacement in relation to the life expectancy provided we treat the patients with serious, in a way „symptomatic“

growth hormone deficiency and without obvious contraindications (active malignant disease, labile diabetes mellitus).

Keywords: Growth hormone deficiency in adulthood, insulin tolerance test

Published: July 15, 2013  Show citation