Interní Med. 2013; 15(6-7): 225-228

Asymptomatic duodenal ulcer penetration into the liver of a patient with anticoagulant therapy

MUDr.Mgr.Jaroslav Maceček, Ph.D.1, MUDr.Jiří Tůma1, MUDr.Lukáš Prucek1, MUDr.Jindřiška Judasová2, MUDr.Dagmar Nedvědová2
1 Interní oddělení a gastroenterologická ambulance, Středomoravská Nemocniční a.s. &ndash, odštěpný závod Nemocnice

Case report describes a patient with accidentally discovered hypoechogenic liver mass diagnosed by abdominal ultrasonography and confirmed

by CT scan and also the relationship to the wall of the duodenum was founded. The patient was examined and gradually the malignancy,

abscess or an inflammatory disease of the duodenum with the liver fistula were excluded. Esophagogastroduodenoscopy was done and the

deep duodenal bulb ulcer with penetration into the liver was detected. It was decided about conservative therapeutical approach with the

deployment of the maximum oral dose of proton pump inhibitors with full condition restitution. The patient was asymptomatic throughout.

Keywords: ulcer penetration, proton pump inhibitors, hypoechogenic liver mass

Published: July 15, 2013  Show citation

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Maceček J, Tůma J, Prucek L, Judasová J, Nedvědová D. Asymptomatic duodenal ulcer penetration into the liver of a patient with anticoagulant therapy. Interní Med. 2013;15(6-7):225-228.
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References

  1. Somi MH, Tarzamni MK, Farhang S, Eftekhaar-Sadat AT. Liver mass due to penetration of a silent duodenal ulcer. Arch Iran Med 2007; 10(2): 242-245.
  2. Fujihara S, Mori H, Nishiyama N, Kobara H, Masaki T. Giant gastric ulcer penetrating into the pancreas. Arab J Gastroenterol 2012; 13(3): 158-160. Go to original source... Go to PubMed...
  3. Singh T, Mendelson R. Case report: Confined penetration of a duodenal ulcer causing pancreatitis. J Med Imaging Radiat Oncol 2010; 54(2): 171. Go to original source... Go to PubMed...
  4. Milosavljevic T, Kostić-Milosavljević M, Jovanović I, Krstić M. Complications of peptic ulcer disease. Dig Dis 2011; 29 (5): 491-493. Go to original source... Go to PubMed...
  5. Wurm G, Saers T, Weber M, Krakamp B. Uncommon condition of the upper gastrointestinal tract: double pylorus]. Z Gastroenterol 2009; 47(2): 220-226. Go to original source... Go to PubMed...
  6. Lee SJ, Shin DH, Hwang HJ, Kim JY, Pak HN, Lee MH, Joung B. Bleeding risk and major adverse events in patients with previous ulcer on oral anticoagulation therapy. Am J Cardiol. 2012; 110(3): 373-377. Go to original source... Go to PubMed...
  7. Younossi ZM, Strum WB, Schatz RA, Teirstein PS, Cloutier DA, Spinks TJ. Effect of combined anticoagulation and low-dose aspirin treatment on upper gastrointestinal bleeding. Dig Dis Sci 1997; 42(1): 79-82. Go to original source... Go to PubMed...
  8. Ahsberg K, Höglund P, Kim WH, von Holstein CS. Impact of aspirin, NSAIDs, warfarin, corticosteroids and SSRIs on the site and outcome of non-variceal upper and lower gastrointestinal bleeding. Scand J Gastroenterol 2010; 45(12): 1404-1415. Go to original source... Go to PubMed...
  9. Nakamura K, Akahoshi K, Ochiai T, Komori K, Haraguchi K, Tanaka M, Nakamura N, Tanaka Y, Kakigao K, Ogino H, Ihara E, Akiho H, Motomura Y, Kabemura T, Harada N, Chijiiwa Y, Ito T, Takayanagi R. Characteristics of hemorrhagic peptic ulcers in patients receiving antithrombotic/nonsteroidal antiinflammatory drug therapy. Gut Liver 2012; 6(4): 423-426. Go to original source... Go to PubMed...
  10. Le Ray I, Barkun AN, Vauzelle-Kervroëdan F, Bardou M. Failure to Renew Prescriptions for Gastroprotective Agents to Patients on Continuous Nonsteroidal Anti-Inflammatory Drugs Increases Rate of Upper Gastrointestinal Injury. Clin Gastroenterol Hepatol 2013; S1542-3565(13): 00008-6. Go to original source... Go to PubMed...
  11. Wierzchowski P, Dąbrowiecki S, Szczęsny W. Urgent endoscopy in elderly patients with non-variceal upper gastrointestinal bleeding. Wideochir Inne Tech Malo Inwazyjne 2012; 7(4): 246-250. Go to original source... Go to PubMed...
  12. Zhang L, Ren JW, Wong CC, Wu WK, Ren SX, Shen J, Chan RL, Cho CH. Curr Med Chem. Effects of cigarette smoke and its active components on ulcer formation and healing in the gastrointestinal mucosa 2012; 19(1): 63-69. Go to original source...
  13. Zimandlová D, Bureš J. Současné možnosti léčby peptických vředů. Interní medicína pro praxi 2012; 14(2): 51-54.
  14. Abboud B, Daher R, Boujaoude J. Digestive manifestations of parathyroid disorders. J Gastroenterol 2011; 17(36): 4063-4066. Go to original source... Go to PubMed...
  15. Inuzuka T, Okabe Y, Nishikawa H, Osaki Y. A case of Zollinger-Ellison syndrome diagnosed by duodenal ulcer perforation into the gallbladder. Gastrointest Endosc 2013; S0016-5107(12): 02996-3. Go to original source... Go to PubMed...
  16. Naoe H, Iwasaki H, Kawasaki T, Ozaki T, Tsutsumi H, Okuda A, Konoe T, Nonaka K, Kaku E, Shono T, Yokomine K, Sakurai K, Iyama K, Hirota M, Sasaki Y. Primary hepatic gastrinoma as an unusual manifestation of zollinger-ellison syndrome. Case Rep Gastroenterol. 2012; 6(3): 590-595. Go to original source... Go to PubMed...
  17. Molaei M, Minakari M, Pejhan Sh, Mashayekhi R, Modaress Fatthi AR, Zali MR. Intestinal leishmaniasis in acquired immunodeficiency syndrome. Iran Red Crescent Med J. 2011; 13(5): 348-351. Go to PubMed...
  18. Gupta N. A rare cause of gastric perforation-Candida infection: a case report and review of the literature. J Clin Diagn Res 2012; 6(9): 1564-1565. Go to original source... Go to PubMed...
  19. Moriyama T, Matsumoto T. Esophagogastroduodenal mucosal lesions in patients with inflammatory bowel disease. Nihon Rinsho 2012; 70(1): 249-252. Go to PubMed...
  20. Krejčí I. Vředová choroba gastroduodena. Med Pro Praxi 2007; 5: 209-210.
  21. Pavlovic Markovic A, Rösch T, Alempijevic T, Krstic M, Tomic D, Dugalic P, Sokic Milutinovic A, Bulajic M. Endoscopic ultrasound for differential diagnosis of duodenal lesions. Ultraschall Med. 2012; 33(7): 210-217. Go to original source... Go to PubMed...
  22. Wijdicks EF. Cushing's ulcer: the eponym and his own. Neurosurgery. 2011; 68 (6): 1695-1698. Go to original source... Go to PubMed...
  23. Balalau C, Popa F, Negrei C, Andreianu P. Therapeutic attitude in perforated stress ulcer. Rev Med Chir Soc Med Nat Iasi 2011; 115(4): 1119-1123. Go to PubMed...
  24. Ginzburg L. Esophageal ulceration: a complication of radiofrequency ablation treatment of atrial fibrillation. Gastrointest Endosc. 2009; 70(3): 551-552. Go to original source... Go to PubMed...
  25. Kwok A, Faigel DO. Management of anticoagulation before and after gastrointestinal endoscopy. Am J Gastroenterol. 2009; 104(12): 3085-3097. Go to original source... Go to PubMed...
  26. Bureš J, Kopáčová, M, Koupil I, et al. Epidemiology of Helicobacter pylori infection in the Czech Republic. Helicobacter 2006; 11(1): 56-65. Go to original source... Go to PubMed...
  27. Bureš J, Kopčáčová M, Rejchrt S. Pokles prevalence infekce Helicobacter pylori v České republice. Čas Lék Čes 2008; 147(5): 255-257.




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