Interní Med. 2013; 15(6-7): 236-239
Perioperative management of patients on anticoagulant therapy involves assessing and balanci ng individual risks for thromboembolism
and bleeding. Discontinuing peroral anticoagulant therapy is usually necessary for most surgical procedures but increases the risk
of thrombotic events. Temporary periprocedural substitution of low-molecular-weight heparin or unfractionated heparin in place of
warfarin, is an effective means of reducing the risk of thromboembolism but may increase the risk of bleeding. The timing of warfarin
withdrawal and timing of the preoperative and postoperative apllication of parenenteral anticoagulant are critical to balancing these risks.
Published: July 15, 2013 Show citation