Interní Med. 2013; 15(11-12): 368-371

Cushing´s syndrome

prof.MUDr.Michal Kršek, CSc.
3. interní klinika-klinika endokrinologie a metabolizmu 1. LF UK a VFN v Praze

Cushing’s syndrome is a disorder characterized by increased autonomous production of cortisol and increased effects of cortisol on

peripheral tissues. It is a rare disorder; however it seriously affects patients and is connected with increased morbidity and mortality.

Moreover, its aetiology is variable and its differential diagnosis belongs to the most difficult ones in clinical endocrinology. Early determination

of correct diagnosis is essential for prognosis of patients. The article summarizes current approach to the diagnosis and

differential diagnosis of Cushing’s syndrome.

Keywords: Cushing’s syndrome, cortisol, diagnosis, differential diagnosis

Published: December 1, 2013  Show citation

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Kršek M. Cushing´s syndrome. Interní Med. 2013;15(11-12):368-371.
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References

  1. Kršek M, Hána V, et al. Cushingův syndrom. Praha: Galén 2006: 144.
  2. Kršek M. Cushingův syndrom a možnosti jeho řešení v roce 2012. Remedia 2012; 22: 386-392.
  3. Newell-Price J, Trainer P, Bessser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocrine Reviews 1998; 19: 647-672. Go to original source... Go to PubMed...
  4. Nieman LK, Biller BMK, Findling JW, Newell-Price J, Savage MO, Stewart PM, Montori VM. The Diagnosis of Cushing´s Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008; 93: 1526-1540. Go to original source... Go to PubMed...
  5. Ross EJ, Linch DC. Cushing's syndrome - Killing disease: Discriminatory value of signs and symptoms aiding early diagnosis. Lancet 1982; 2: 646-649. Go to original source... Go to PubMed...




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