Interní Med. 2014; 16(4): 159-162
Herpes zoster virus and ocular involvement
- 1 Soukromá oční ambulance &ndash, Ophthos s. r. o., Praha
- 2 Oční klinika, 1. lékařská fakulta, Univerzita Karlova v Praze a VFN v Praze
The Herpes zoster virus is DNA virus. After the initial infection has been treated, the virus remains dormant in a ganglion until reactivation
of the latent virus resulting in shingles – Herpes zoster. Herpes zoster ophthalmicus is defined as a classic dermatomal rash in the
ophthalmic division of the trigeminal nerve. It represents approximately 10 to 25 percent of all cases of herpes zoster. Patients with
herpes zoster may develop conjunctivitis, keratitis, uveitis and retinal disorders. Lasting effects of this infection may include chronic
eye inflammation, neuropathic pain or even loss of vision. Antiviral drugs such as aciclovir, famciclovir and valaciclovir remain the
mainstay of treatment and can be effective in preventing ocular disability if treatment is started within 72 hours after the onset of skin
manifestations. Early diagnosis and treatment of ophthalmic herpes zoster are important prevention of visual impairment. When skin
manifestation is present it is advised to also run appropriate ophthalmological examinations. This work deals with the herpes zoster
virus, the clinical picture, diagnosis and therapy.
Keywords: Herpes zoster virus, herpes zoster ophthalmic, keratitis, uveitis, retinitis, antiviral drugs
Published: June 1, 2014 Show citation
References
- Shaikh, S., Christopher, N.TA. Evaluation and Management of Herpes Zoster Ophthalmicus. Stanford University Medical Center, Stanford, California, Am Fam Physician. 2002 Nov 1;66 (9): 1723-1730.
- Kanski, J.J. Clinical Ophtalmology a systematic approach. 6th edition. Elsevier limited, 2007, s. 262-270, 477-482.
- Rozsíval, P. a spol. Infekce oka. Praha: Grada Publishing, a.s., 2003, 228 s.
- Kuchynka, P. a kol. Oční lékařství. Praha: Grada Publishing, a.s. 2007, s. 2-6, 186, 226-230, 435-438.
- Pavan-Langston, D. et al. Advances in the management of ocular herpetic disease. Florida. 2011, 20 s.
- Kolektiv autorů. Diagnostika a léčba očních chorob v praxi. The Wills eye manual. Praha: Triton, 2004, 620 s.
- Boguszaková, J., Říhová, E., Krásný, J. Oční záněty. Praha: Maxdorf, 2007, 96 s.
- Jeníčková, D. Infekční uveitidy. In: Říhová, E. a kol. Uveitidy. Praha: Grada Publishing, a.s., 2009, s. 27-32.
- Čihák, R. a kol. Periferní nervy. In: Čihák, R. a kol. Anatomie 3. Praha: Grada Publishing, a.s., 2009, s. 473-475.