Interní Med. 2014; 16(5): 199-201

Granulomatosis with polyangiitis

MUDr.Kateřina Martinková¹, MUDr.Ivo Valkovský, Ph.D.^1,2, MUDr.Petr Handlos^2,3

¹ Interní klinika, Fakultní nemocnice Ostrava

² Lékařská fakulta Ostravské univerzity

³ Ústav soudního lékařství, Fakultní nemocnice Ostrava

Granulomatosis with polyangiitis (formerly known as Wegener‘s granulomatosis) is a necrotizing vasculitis that affects the small vessels,

especially those of the respiratory system, and kidneys via the formation of granulomas, manifesting as necrotizing glomerulonephritis.

Our case report presents the case of 56 years old man, who was sent to the Department of Internal Medicine at the University Hospital

of Ostrava from a regional hospital because of a persisting intermittent fever. The patient´s clinical characteristics included bilateral

perimaleolar oedema, mild weight loss, subjective complaints of an upper respiratory tract infection lasting for several months, and

migrating pain involving the large joints. The case is highlighting the polymorphic symptomatology of this relatively rare disease.

Keywords: granulomatosis with polyangiitis, Wegener‘s granulomatosis, fever

Published: November 1, 2014  Show citation