Interní Med. 2015; 17(1): 26-27
Treatment of chronic hepatitis C is undergoing extraordinary changes in the past 4 years. Direct-Acting Antivirals (DAA) are gradually
introducing into routine clinical practice either in combination with pegylated interferon and ribavirin, or in interferon-free or even
ribavirin-free regimes. Sofosbuvir, simeprevir, and fixed combination of sofosbuvir and ledipasvir have been already approved in the
European Union and United States. Daclatasvir has been additionally approved in the European Union. The advantages of DAA are high
potency and minimum of adverse events.
Published: February 27, 2015 Show citation