Interní Med. 2015; 17(4): 165-167

Thyroid hormones in clinical practice

prof.MUDr.Václav Zamrazil, DrSc.
Endokrinologický ústav Praha
Subkatedra endokrinologie IPVZ, Praha

Thyroid hormones are widely used for substitution of hypothyroidism, in some cases for supresion of TSH level. For treatment thyroxin

(tetrajodotyronin) is used in most of patients. When dejodation of thyroxine (productive of trijodothyronine) is supposed to be insuficient,

the combination of thyroxine and trijodotyronine (13 : 1) should be considered. Several new methods of treatment with thyroid hormones

are currently evaluated for clinical practice.

Keywords: thyroxine, trijodothyronine, substitution of hypothyroidism, supresion of TSH level, new perspectives of treatment

Published: September 19, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Zamrazil V. Thyroid hormones in clinical practice. Interní Med. 2015;17(4):165-167.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Zamrazil V. Onemocnění štítné žlázy v klinické praxi POSTGRAD MED 2013; 15: 720-729.
    2. Zamrazil V. Hypotyreoza v Stárka L. (ed) Lékařské repetitorium Endokrinologie, Praha, Triton 2010: 144-147.
    3. Vlček P. Nádory štítné žlázy v Stárka L. (ed) Lékařské repetitorium Endokrinologie, praha, Triton 2010: 150-153.
    4. Jouklas J, Bianeo AC, Bauer AJ, et al. Guedelines for the treatment of hypothyroidism Thyroid 2014; 24: 1670-1751. Go to original source... Go to PubMed...
    5. Garber JR, Cobin PH, Gharib H, et al. Clinical practice guidelines for hypothyroidism in adults Thyroid 2012; 22: 1200-1233. Go to original source... Go to PubMed...
    6. Escobar-Morrale HF, Botella-Carretero JI, Gomez-Bueno M: Thyroid hormone replacement therapy in primary hypothyroidism. Ann Intern Med 2005; 142: 412-424. Go to original source... Go to PubMed...
    7. Melis L, Vanden berghe G. Thyroid axis function and dysfunction in clinical illnes Best Pract Res Clin Endocrinol Metab 2011; 25: 745-757. Go to original source... Go to PubMed...
    8. Vanden Berge G. Non-thyroid illnes in the ICU: a syndrome with different faces Thyroid 2014; 249: 1456-1465. Go to original source... Go to PubMed...
    9. Balhara B, Misra M, Levitsky LL. Clinical monitoring guidelines for congenital hypothyroidism J Pediatr 2011; 158: 532-537. Go to original source... Go to PubMed...
    10. Wartofsky L. Levotyroxine therapy for hypothyroidism Arch Internal Med 2005; 165: 1683-1684. Go to original source... Go to PubMed...
    11. Wirsinga W, Duntas LA, Fadeyev VV, et al. ETA guidelines: The use of LT4+LT3 in the treatment of thyroidism Eur Thyroid 2012; 1: 55-71. Go to original source... Go to PubMed...
    12. Bervenga S, Bartolone L, Pappalardo MT, et al. Altered intestinal absorption of lenothyroxine consed for coffee Thyroid 2008; 18: 293-301. Go to original source... Go to PubMed...
    13. Zamfiresen I, Carlson HE. Absorption of levothyroxine when concomitant coadministration with various calcim formulas Thyroid 2011; 21: 483-480. Go to original source... Go to PubMed...
    14. Grosinski-Glasberg S, Fraser A, Nahshoni E, et al. Thyroxine a triindothyroxine combination therapy versus thyroxine monotherapy for clinical hypothyroidism J Clin Endocrinol Metab 2006; 91: 2592-2599. Go to original source... Go to PubMed...
    15. Wirsinga WM. Paradigma shift in thyroid replacement therapies for hypothyroidism Nt Rev Endocrinol 2014; 10: 164-174. Go to original source... Go to PubMed...
    16. Nygaard B. 2012 ETA guidelines: The use of L-T4 + L-T3 in the treatment of hypothyroidism ETA MERCK SYMPOSIUM, PISA 2012.
    17. Celi FS, Zemskova M, Linderman jD, et al. Metabolic effects of liothyronine therapy in Hypothyroidism J Clin Endocrinol Metab 2011; 96: 3466-3473. Go to original source... Go to PubMed...
    18. Merubu Ayers SD, Winnier G, Webb P. Thyroid hormone analogues: where do we stand in 2013? Thyroid 2013; 23: 1333-1344. Go to original source... Go to PubMed...
    19. Hollenberg AN, Jameson JR: metabolism of thyroid hormone action s. 1861-1872 v Endocrinology 5. vydání J. De Groot LJ, Jameson JL (ed) Elseviers Saunders, Philadelphia 2006.
    20. Karmisholt J, Andersen S, Lauberg P. Weight low after therapy of hypothyroidism is mainly counsed by excretion of exces body weight associated with myxedema J Clin Endocrinol Metab 2011; 96: E99-E103. Go to original source... Go to PubMed...
    21. Rivlin TLS: Therapy of obesity with hormones New Engl J Med 1975; 292: 26-29. Go to original source... Go to PubMed...
    22. O Grady MJ, Cody D. Subclinical hypothyroidism in childhood Arch Dis Clied 2011; 96: 280-284. Go to original source... Go to PubMed...

    Return to the content


    Internal Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.