Interní Med. 2017; 19(4): 204-208 | DOI: 10.36290/int.2017.036

Herpetic infections of the central nervous system

MUDr. Lenka Fašaneková, MUDr. Matúš Mihalčin, MUDr. Martina Pýchová, prof. MUDr. Petr Husa, CSc.
Klinika infekčních chorob, FN Brno, Lékařská fakulta Masarykovy univerzity, Brno

Herpesviruses are the most complex viruses infecting humans. They usually establish latent infections and persist in the organismfor lifelong. Herpesviruses can cause neuroinfections of various severity. Hemorrhagic encephalitis is the most serious neurologicalcomplication and despite available treatments, the disease still has high morbidity and mortality. Cerebrospinal fluid analysis, usingcytology and polymerase chain reaction (PCR) for direct proof of the virus, is considered the gold standard for the diagnostics. Inthis article we summarized the current diagnostic and therapeutic approaches used for management of herpetic neuroinfections.

Keywords: herpesviruses, encephalitis, meningitis, therapy, diagnostics

Published: November 1, 2017  Show citation

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Fašaneková L, Mihalčin M, Pýchová M, Husa P. Herpetic infections of the central nervous system. Interní Med. 2017;19(4):204-208. doi: 10.36290/int.2017.036.
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