Interní Med. 2017; 19(5): 237-245 | DOI: 10.36290/int.2017.039

Possibilities for treatment of osteoporosis

MUDr. Olga Růžičková

Revmatologický ústav Praha

Osteoporosis is a systemic metabolic dissease with mass incidence especially in older population. 33% of women and 15% of menolder 50 years and 47% of women, 39% of men older than 70 years suffer from osteoporosis in Czech Republic, totaly 6% of population.The femoral fracture risk is 9-18% for women and 3-6% of men in the age of 50 years of age. 20-30% of patients after thisfracture will die during the first year after the fracture, 30-40% will stay dependent on someone else. The mortality is increasingwith age after the proximal femoral fracture and the highest is during the first year after the fracture. The real target in treatmentof osteoporosis is prevention of fractures. The basis of prevention and treatment of osteoporosis is adequat suplemntation odcalcium and vitamin D. Drugs of the first choice are bisphosphonates. The second choice in case of failure of antiresorptive drugsis denosumab. Patient in the highest risk of fracture have been treated by derivates of parathormon.

Keywords: osteoporosis, calcium, vitamin D, bisphosphonates, parathormon, romosozumab, abaloparatid

Published: December 1, 2017  Show citation