Interní Med. 2017; 19(5): 262-265 | DOI: 10.36290/int.2017.059
Addison´s disease – do we think of it in differential diagnosis?
- Interní odělení Nemocnice Na Homolce, Praha
Addison´s disease or primary adrenocortical insufficiency is a rare condition, in which adrenal cortex is destructed by infection,metastasis or degenerative process or adrenal glands were removed by surgical intervention. The correct diagnosis can be hidingfor a long time due to its presentation with non-specific symptoms. The early diagnosis and starting lifelong steroid replacementtherapy promptly improves patient´s condition and avoids complications arising from the lack of adrenocortical hormons. The novelthereapeutic approaches in autommune Addison´s disease is immunomodulatory and regenerative medicine, yet in clinical studies.
Keywords: Addison, diagnosis, kortisol, steroid replacement therapy, immonomodulatory and regenerative medicine
Received: September 3, 2018; Accepted: September 23, 2018; Published: December 1, 2017 Show citation
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