Interní Med. 2018; 20(5): 247-252 | DOI: 10.36290/int.2018.043
Osteoporosis – 1st part, etiopathogenesis, risk factors and diagnostics
- Ústav farmakologie LF UP a FN Olomouc
Osteoporosis is considered to be a disease prevails highly not only in the most developed industrial countries. As a chronic diseaseof the skeleton it is characterised by the decrease of bone density with deterioration of bone microstructure. Lowered bonestrength is a result of quantitative and qualitative changes in the bone mass and this contributes to higher risk of fractures. Creationof the highest level of bone mass is the most important preventative factor. This can be achieved by consistent and appropriatephysical activity and sufficient nutrition high in calcium, vitamin D and proteins. The diagnosis of osteoporosis is achieved eitherby laboratory tests, or mainly by dual-energy X-ray absorptiometry. Amongst women osteoporosis is mainly caused by estrogenicdeficits. Among men the cause is mainly due to lack of testosterone. Secondary osteoporosis is caused mainly by glucocorticoidtherapy, malnutrition, immobility, liver disease and kidney disease.
Keywords: bone, osteoporosis, risk factors, diagnostics
Published: December 1, 2018 Show citation
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