Interní Med. 2019; 21(2): 125-127
How to manage mild hypertension?
- II. interní klinika, LF a FN v Plzni
Grade 1 hypertension is defined as a blood pressure of 140–159/90–99 mmHg. The pharmacological antihypertensive treatment is indicated in patients with manifest cardiovascular complications or in patients with a high cardiovascular risk. Recently published data shows that also patients with low cardiovascular risk might benefit from antihypertensive treatment. The treatment can be started either with monotherapy or with dual combination in low doses preferably using fixed dose combination which are associated with higher adherence to treatment. In most clinical situations we should use combination of angiotensin-converting enzyme inhibitor of angiotensin receptor blocker with calcium channel blocker. Dual combination of perindopril with amlodipine has the most data showing its beneficial effect from all fixed dose combinations available in the Czech market.
Keywords: grade 1 hypertension, high normal blood pressure, fixed dose combination, cardiovascular risk, perindopril, amlodipine
Published: May 10, 2019 Show citation
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