Interní Med. 2019; 21(4): 217-222 | DOI: 10.36290/int.2019.033

News in immunomodulatory treatment with bacterial lysates in allergy and asthma

doc. MUDr. Jaromír Bystroň, CSc.
Oddělení alergologie a klinické imunologie, Fakultní nemocnice Olomouc

The author presents the latest findings on the use of bacterial lysates in allergic diseases and bronchial asthma. It presents the
latest developments in both experimental and clinical studies on the mechanism of action, indications and risks of administration
of these products. There are also pharmacoeconomic studies that confirm the utility of bacterial lysates in patients with allergies.
At the same time, it also contemplates the main mechanisms by which bacterial lysates can influence the course and intensity
of allergic inflammation.

Keywords: bacterial lysates, immunomodulation, allergy, bronchial asthma

Published: November 1, 2019  Show citation

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Bystroň J. News in immunomodulatory treatment with bacterial lysates in allergy and asthma. Interní Med. 2019;21(4):217-222. doi: 10.36290/int.2019.033.
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References

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  2. Bystroň J. Bakteriální imunomodulátory - přirozené stimulátory imunitního sytému. SLK i.med.sk. 2012.
  3. Bystroň J., a spol. Účinnost a bezpečnost perorálního bakteriálního imunomodulátoru Olimunovac u pacientů s častými infekcemi dýchacích cest. (Observační multicentrická studie). Alergie, 2011, 13, No 1, 58-66.
  4. Bystroň J. Využití bakteriálních lyzátů v praxi. Medicína pro praxi 2012, 9, č.8-9, 336-341.
  5. Morandi B, Agazzi A, et al. A mixture of bacterial mechanical lysates is more efficient than single strain lysate and of bacterial-derived soluble products for the induction of an activating phenotype in human dendritic cells. Immunol. Lett 2011,138(1): 86-91. Go to original source... Go to PubMed...
  6. Guani-Guera E, Negrete-Garcia MC Montez-Vizuet R, et al. Human ?-defensin-2 induction in nasal mucosa after administration of bacterial lysates. Arch.Med.Res. 2011, Apr: 42(3): 189-194. Go to original source... Go to PubMed...
  7. Braido F, Schenone G, Canonica GW, et al. The relationship between mucosal immunoresponse and clinical outcome in patients with recurrent upper respiratory tract infections treated with a mechanical bacterial lysate. J.Biol.Regul.Homeost.Agents 2011: 25(3): 477-485. Go to PubMed...
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