Interní Med. 2018; 20(1): 7-9 | DOI: 10.36290/int.2018.002

Sleep apnoea syndrome and gastroesophageal reflux disease in clinical and pathophysiological context

MUDr. Samuel Genzor1, MUDr. Jan Gregar, Ph.D.2, MUDr. Milada Hobzová1
1 Klinika plicních nemocí a tuberkulózy Fakultní nemocnice Olomouc
2 Klinika gastroenterologická a hepatologická Fakultní nemocnice Olomouc

Obstructive sleep apnoea syndrome is the most common sleep breathing disorder. Beside unpleasant daytime and night symptoms,there is an important relationship with other diseases – cardiovascular, pulmonary and also gastroesophageal reflux. Theimportant cause of sleep apnoea and gastroesophageal reflux is obesity and both diseases are more common in the male population.There is an interplay between apnoea and obesity in pathogenesis of the gastric fluids reflux. The therapy of patientsshould be complex – focused on weight reduction and treatment of sleep apnoea and reflux.

Keywords: sleep apnoea syndrome, gastroesophageal reflux, comorbidities, pathophysiology

Published: March 1, 2018  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Genzor S, Gregar J, Hobzová M. Sleep apnoea syndrome and gastroesophageal reflux disease in clinical and pathophysiological context. Interní Med. 2018;20(1):7-9. doi: 10.36290/int.2018.002.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005; 54(5): 710-717. Go to original source... Go to PubMed...
    2. Zanation AM, Senior BA. The relationship between extraesophageal reflux (EER) and obstructive sleep apnea (OSA). Sleep Medicine Reviews, 2005; 9(6): 453-458. Go to original source... Go to PubMed...
    3. Ferini-Strambi L, Fantini ML, Castronovo C. Epidemiology of obstructive sleep apnea syndrome. Minerva Medica 2004, 95(3): 187-202.
    4. Parati G, Ochoa JE, Bilo G, Mattaliano P, Salvi P. Obstructive sleep apnea syndrome as a cause of resistant hypertension. Hypertens Res. 2014; 37(7): 601-613. Go to original source... Go to PubMed...
    5. Destors M, Tamisier R, Baguet JP, Levy P, Pepin JL. [Cardiovascular morbidity associated with obstructive sleep apnea syndrome]. [Article in French] Rev Mal Respir. 2014; 31(4): 375-385. Go to original source... Go to PubMed...
    6. Gilani S, Quan SF, Pynnonen MA, Shin JJ. Obstructive Sleep Apnea and Gastroesophageal Reflux: A Multivariate Population-Level Analysis. Otolaryngol Head Neck Surg. 2016; 154(2): 390-395. Go to original source...
    7. Kim Y, Lee YJ, Park JS, Cho YJ, Yoon HI, et al. Associations between obstructive sleep apnea severity and endoscopically proven gastroesophageal reflux disease. Sleep Breath. 2017 Jul 7. [epub ahead of print]. Go to original source...
    8. Shepherd K, Orr W. Mechanism of Gastroesophageal Reflux in Obstructive Sleep Apnea: Airway Obstruction or Obesity? J Clin Sleep Med. 2016; 12(1): 87-94. Go to original source...
    9. Demeter P, Pap A. The relationship between gastroesophageal reflux disease and obstructive sleep apnea. J Gastroenterol. 2004; 39(9): 815-820. Go to original source... Go to PubMed...
    10. Kuribayashi S, Kusano M, Kawamura O, Shimoyama Y, Maeda M, et al. Mechanism of gastroesophageal reflux in patients with obstructive sleep apnea syndrome. Neurogastroenterol Motil. 2010; 22(6): 611-172. Go to original source...
    11. Orr WC, Robert JJ, Houck JR, Giddens CL, Tawk MM. The effect of acid suppression on upper airway anatomy and obstruction in patients with sleep apnea and gastroesophageal reflux disease. J Clin Sleep Med. 2009; 5(4): 330-334. Go to original source...
    12. Jobin V, Champagne V, Beauregard J, Charbonneau I, McFarland DH, el al. Swallowing function and upper airway sensation in obstructive sleep apnea. J Appl Physiol 2007; 102: 1587-1594. Go to original source... Go to PubMed...
    13. Hosogane N, Watenabe K, Yagi M, Kaneko S, Toyama Y, et al. Scoliosis is a Risk Factor for Gastroesophageal Reflux Disease in Adult Spinal Deformity. Clin Spine Surg. 2017; 30(4) : 480-484. Go to original source...
    14. Jung H, Choung RS, Talley NJ. Gastroesophageal Reflux Disease and Sleep Disorders: Evidence for a Causal Link and Therapeutic Implications. Journal of Neurogastroenterology and Motility 2010; 16(1): 22-29. Go to original source...
    15. Vela MF, Kramer JR, Richardson PA, Dodge R, El-Serag HB. Poor sleep quality and obstructive sleep apnea in patients with GERD and Barrett's esophagus. Neurogastroenterol Motil. 2014; 26(3): 346-352. Go to original source... Go to PubMed...
    16. Tamanna S, Campbell D, Warren R, Ullah MI. Effect of CPAP Therapy on Symptoms of Nocturnal Gastroesophageal Reflux among Patients with Obstructive Sleep Apnea. J Clin Sleep Med. 2016; 12(9): 1257-1261. Go to original source...
    17. Wang L, Liu JX, Qin YX, Wang HM, Liu HY. [Research on the relationship between obstructive sleep apnea hypopnea syndrome and gastroesophageal reflux]. [Article in Chinese] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009; 44(1): 26-30. Go to PubMed...
    18. Zhang C, Wang Z, Wu J, Ji F, Gao X, et al. The Laparoscopic Nissen Fundoplication Eliminates Obstructive Sleep Apnea Syndrome Due to Gastroesophageal Reflux Disease. Indian J Surg. 2013; 75(Suppl 1): 326-328. Go to original source... Go to PubMed...
    19. Rassameehiran S, Klomjit S, Hosiriluck N, Nugent K. Meta-analysis of the effect of proton pump inhibitors on obstructive sleep apnea symptoms and indices in patients with gastroesophageal reflux disease. Proc (Bayl Univ Med Cent). 2016; 29(1): 3-6. Go to original source... Go to PubMed...
    20. Garg H, Priyadarshini P, Aggarwal S, Agarwal S, Chaudhary R. Comparative study of outcomes following laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in morbidly obese patients: A case control study. World J Gastrointest Endosc. 2017; 9(4): 162-170. Go to original source...

    Return to the content


    Internal Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.