Interní Med. 2019; 21(3): 184-186

How to deal with non-specificity of tumor markers?

RNDr. Lenka Zdražilová‑Dubská, Ph.D.1, MUDr. Beatrix Bencsiková, Ph.D.2, doc. MUDr. Dalibor Valík, Ph.D.1
1 Oddělení laboratorní medicíny, Masarykův onkologický ústav, Brno
2 Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno

Here we aim to review sources of unspecific or false elevation of soluble tumour markers. We suggest how to approach results of
elevated tumour markers in clinical practice.

Keywords: tumour markers, specificity, interpretation

Published: June 30, 2019  Show citation

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Zdražilová‑Dubská L, Bencsiková B, Valík D. How to deal with non-specificity of tumor markers? Interní Med. 2019;21(3):184-186.
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    References

    1. Valík D, Nekulová M, Zdražilová Dubská L, et al. Doporučení České společnosti klinické biochemie (ČSKB ČLS JEP) České onkologické společnosti (ČOS ČLS JEP) České společnosti nukleární medicíny (ČSNM ČLS JEP) - sekce imunoanalytických metod k využití nádorových markerů v klinické praxi. Klin. Biochem. Metab. 2014; 22: 18.
    2. Greplova K, Selingerova I, Valik D, et al. [Lactate Dehydrogenase - Old Tumour Marker in the Light of Current Knowledge and Preanalytic Conditions]. Klin Onkol 2017; 30: 156-8. Go to PubMed...
    3. Chovanec J, Selingerova I, Greplova K, et al. Adjustment of serum HE4 to reduced glomerular filtration and its use in biomarker-based prediction of deep myometrial invasion in endometrial cancer. Oncotarget 2017; 8: 108213-22. Go to original source... Go to PubMed...

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